Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program

by: Iola Bonggay

The Food and Drug Administration, otherwise referred to as FDA, is a federal government agency operating within the United States Department of Health and Human Services that is primarily responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs.

The grants and programs of the FDA are all geared towards the achievement of its primary agency mission which is to "protect consumers and enhance public health by maximizing compliance of FDA regulated products and minimizing risk associated with those products."

In this capacity, the Food and Drug Administration has recently established the Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program in an attempt to study the effects of various physicochemical properties of ophthalmic suspensions and emulsions on ocular bioavailability.

To this effect, the program will cover the key physicochemical properties which may impact clearance, distribution, and drug release; specifically globule/particle size distribution, surface change, osmolality, pH, viscosity, and dispersibility.

It is known that there are several kinds of opthalmic drugs which are available in the market today. The goal of this study is to determine which manufacturing differences may result in physicochemical differences which in turn may affect clearance, distribution, and release of the drug.

  (continued...)

Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program
  Page 2

About The Author Iola Bonggay is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. She also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Resources

category - Health Grants

Competitive Revision for Technology Development Within Biomedical Technology Research Centers Program
The National Institutes of Health has formed a partnership with the National Center for Research Resources (NCRR) in an attempt to establish the Competitive Revision for Technology Development Within Biomedical Technology Research Centers Program.

---

American Schools and Hospitals Abroad Program
Much of the international aid provided by the United States government goes to support education and healthcare efforts around the world. Many of these programs are design to encourage the spread of American values to other countries.

---

Basic Research on HIV Persistence Program
In keeping with this mission, the National Institutes of Health has recently constituted the establishment of the Basic Research on HIV Persistence Program in an attempt to increase our understanding of the persistence of HIV-1 infections in patients under highly active anti-retroviral therapy (HAART).

---

Lifespan Respite Care Program - Technical Assistance Resource Center
In keeping with this mission, the Administration on Aging has recently announced the constitution of the Lifespan Respite Care Program - Technical Assistance Resource Center wherein it aims to invite applications for a competitive grant opportunity for implementing the requirements of the Technical Assistance Resource Center (TARC) as authorized in the Lifespan Respite Care Act of 2006.

---