Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program

by: Iola Bonggay

The Food and Drug Administration, otherwise referred to as FDA, is a federal government agency operating within the United States Department of Health and Human Services that is primarily responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs.

The grants and programs of the FDA are all geared towards the achievement of its primary agency mission which is to "protect consumers and enhance public health by maximizing compliance of FDA regulated products and minimizing risk associated with those products."

In this capacity, the Food and Drug Administration has recently established the Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program in an attempt to study the effects of various physicochemical properties of ophthalmic suspensions and emulsions on ocular bioavailability.

To this effect, the program will cover the key physicochemical properties which may impact clearance, distribution, and drug release; specifically globule/particle size distribution, surface change, osmolality, pH, viscosity, and dispersibility.

It is known that there are several kinds of opthalmic drugs which are available in the market today. The goal of this study is to determine which manufacturing differences may result in physicochemical differences which in turn may affect clearance, distribution, and release of the drug.

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Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program
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About The Author Iola Bonggay is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. She also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Resources

category - Health Grants

Minor Use Minor Species Development of Drugs: Research Project Grant
The National Institutes of Health has partnered with the U.S. Food and Drug Administration (FDA) and the Center for Veterinary Medicine(CVM) in an effort to establish the Minor Use Minor Species Development of Drugs: Research Project Grant.

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Child Health Research Career Development Award Program
In accordance with this mission, the National Institute of Health has collaborated with the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) in an attempt to establish the Child Health Research Career Development Award Program.

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Research to Advance Vaccine Safety Program
The Centers for Disease Control and Prevention has partnered with the National Institutes of Health and as a result, has developed the Research to Advance Vaccine Safety Program, wherein it seeks to obtain a more thorough understanding vaccine safety.

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Physical and Engineering Sciences in Oncology
The National Science Foundation, in close cooperation the National Cancer Institute, has recently developed the Physical and Engineering Sciences in Oncology Program wherein they intend to obtain a more thorough understanding of cancer disorders with the application of physical and engineering sciences.

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