Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program

by: Iola Bonggay

The Food and Drug Administration, otherwise referred to as FDA, is a federal government agency operating within the United States Department of Health and Human Services that is primarily responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs.

The grants and programs of the FDA are all geared towards the achievement of its primary agency mission which is to "protect consumers and enhance public health by maximizing compliance of FDA regulated products and minimizing risk associated with those products."

In this capacity, the Food and Drug Administration has recently established the Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program in an attempt to study the effects of various physicochemical properties of ophthalmic suspensions and emulsions on ocular bioavailability.

To this effect, the program will cover the key physicochemical properties which may impact clearance, distribution, and drug release; specifically globule/particle size distribution, surface change, osmolality, pH, viscosity, and dispersibility.

It is known that there are several kinds of opthalmic drugs which are available in the market today. The goal of this study is to determine which manufacturing differences may result in physicochemical differences which in turn may affect clearance, distribution, and release of the drug.

  (continued...)

Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program
  Page 2

About The Author Iola Bonggay is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. She also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Resources

category - Health Grants

Telehealth Resource Center Grant Program
The Health Resources and Services Administration has recently constituted the establishment of the Telehealth Resource Center Grant Program, also referred to as the TRCGP.

---

Planning Grants for Hubs of Interdisciplinary Research and Training in Global Environmental and Occupational Health Project
The National Institutes of Health has collaborated with the Centers for Disease Control and Prevention (CDC) to establish the Planning Grants for Hubs of Interdisciplinary Research and Training in Global Environmental and Occupational Health Project.

---

Scale-Up of Care and Support Services for Orphans and Vulnerable Children in Nigeria
The USAID office in Nigeria has recently established a program called Scale-Up of Care and Support Services for Orphans and Vulnerable Children wherein it intends to improve the health and well-being of orphans and vulnerable children in Nigeria by way of developing a sustainable, comprehensive and coordinated program that will potentially help these kids live a normal, and healthy life.

---

Clinical Trials for Organ Transplantation in Children Program
The National Insitutes of Health has formed a partnership with the National Institute of Allergy and Infectious Diseases (NIAID) to establish the Clinical Trials for Organ Transplantation in Children Program wherein both agencies intend to support a group of investigators in their quest of conducting clinical trials regarding pediatric solid organ transplant recipients.

---