Eradication of HIV from CNS Reservoirs: Implications for Therapeutics Grant Program
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b) Basic research that will determine the mechanisms involved in temporal establishment, maintenance, and resurgence of CNS-based HIV-1 reservoirs in relation to the effects and timing of HAART, viral expression, and viral evolution within the patient's brain.

c) The creation of several physiologically relevant animal models and CNS-based cellular assays that recapitulate HIV-1 persistence and latency in the presence of efficient HAART management.

d) Drug screening of potential agents that go beyond the blood-brain barrier and eliminate latent or other sources of residual virus within the CNS.

e) Design of therapeutic strategies aimed towards the eradication of HIV-1 from the CNS.

The funding agencies are set to administer funds in the amount of $2 million to support the initiatives of the program.

The institutions and organizations who will be considered eligible to submit an application under this program are the following:

a) Higher Education Institutions

b) Hispanic-serving Institutions and Historically Black Colleges and Universities (HBCUs)

c) Nonprofit organizations other than institutions of higher education

d) For-Profit Organizations such as Small Businesses

e) State Governments, County Governments, City or Township Governments, and Special District Governments

f) Independent School Districts

g) Public Housing Authorities

h) Faith-based or Community-based Organizations, and Regional Organizations.

Eradication of HIV from CNS Reservoirs: Implications for Therapeutics Grant Program
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About The Author Michael Saunders is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. He also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Resources

category - Health Grants

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The National Institutes of Health has recently established a program entitled Improving Adherence to Treatment Regimens for HIV-Positive Adolescents and Young Adults wherein they intend to kick-off research studies that will create, implement, and evaluate both old and new interventions that are geared towards improving adherence to medical and behavioral regimens for HIV-positive adolescents which are 11 to 21 years old and adults who are 21 to 24 years old.

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Critical Congenital Heart Disease Newborn Screening Demonstration Program
The Health Resources and Services Administration has recently constituted the Critical Congenital Heart Disease (CCHD) Newborn Screening Demonstration Program in order to support and encourage the development, dissemination, and validation of screening protocols and newborn screening infrastructure for point of care screenings that are specific to Critical Congenital Heart Diseases.

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Justice and Mental Health Collaboration Training and Technical Assistance Program
The Office of Justice Programs has recently established the Justice and Mental Health Collaboration Training and Technical Assistance Program (JMHCP), wherein it seeks to increase public safety by encouraging collaboration between criminal justice, juvenile justice, and mental health and substance abuse treatment systems.

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Basic Research on HIV Persistence Program
In keeping with this mission, the National Institutes of Health has recently constituted the establishment of the Basic Research on HIV Persistence Program in an attempt to increase our understanding of the persistence of HIV-1 infections in patients under highly active anti-retroviral therapy (HAART).

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