Mechanisms Mediating Osteoarthritis in Aging
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Initially, the program intends to support research studies that seek to explore the biological mechanisms that are associated with non-inflammatory joint degeneration, as seen in Osteoarthritis. These studies will consequently attempt to determine certain genes, biochemical pathways, and proteins that will contribute to the onset of joint degeneration.

This process will eventually enable researchers to identify the events and processes that will lead to joint degeneration, the functional characterization of proteins that are involved in the process, and the manner by which these gene products contribute to joint degeneration.

As a result, this deepened understanding could potentially lead to the timely prevention and more efficient treatment regimen for people suffering from Osteoarthritis.

The institutions and organizations that will be considered eligible to submit an application under the Mechanisms Mediating Osteoarthritis in Aging are the following:

a) Higher Education Institutions such as Public/State Controlled Institutions of Higher Education and Private Institutions of Higher Education

b) Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions

c) Nonprofit organizations other than institutions of higher education

d) For-Profit Organizations such as Small Businesses

e) State Governments, County Governments, City or Township Governments, Special District Governments, Indian/Native American Tribal Governments (Federally Recognized), and Indian/Native American Tribal Governments (Other than Federally Recognized)

f) Independent School Districts, Public Housing Authorities/Indian Housing Authorities, Native American Tribal Organizations (other than Federally recognized tribal governments), Faith-based or Community-based Organizations, and Regional Organizations.

The Department of Health and Human Services, the mother agency funding the Mechanisms Mediating Osteoarthritis in Aging, is the United States Federal government's leading agency that is largely responsible for ensuring the health of all Americans and the provision of fundamental human services to everyone needing to everyone needing such services.

Mechanisms Mediating Osteoarthritis in Aging
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Additional Resources



category - Health Grants

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The National Institutes of Health has formed a partnership with the National Heart, Lung, and Blood Institute to establish a program that aims to Identify Heart, Lung, and Blood Disease-Causing Variants.


Rheumatic Diseases Research Core Centers Project
The National Institutes of Health, in close cooperation with the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), has established a program entitled Rheumatic Diseases Research Core Centers Project wherein they intend to solicit applications for the development of Research Core Centers concentrating on rheumatic diseases.


Exploratory/Developmental Grants Program for Basic Cancer Research in Cancer Health Disparities
The National Institutes of Health has recently formed a partnership with the National Cancer Institute (NCI) in an effort to constitute the Exploratory/Developmental Grants Program for Basic Cancer Research in Cancer Health Disparities wherein both agencies intend to solicit grant application from various eligible researchers who are interested in conducing basic research studies regarding the biological causes and mechanisms of cancer health disparities.


Small Business Innovation Research Phase IIB Bridge Awards
In line with this mission, the NIH has recently constituted the Small Business Innovation Research Phase IIB Bridge Awards to Accelerate the Development of Cancer Therapeutics, Imaging Technologies, Interventional Devices, Diagnostics, and Prognostics Toward Commercialization Program.






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Edited by: Michael Saunders

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