Mechanisms Mediating Osteoarthritis in Aging

by: TopGovernmentGrants Editorial Staff

The National Institutes of Health, otherwise known as NIH, is an agency operating within the United States Department of Health and Human Services that is primarily responsible for pursuing all of the country's biomedical and health-related research studies.

The actions of the NIH are carefully guided by their overall agency mission which is to obtain a deeper understanding of medical conditions that could potentially help them detect, prevent, diagnose, and treat diseases and disabilities.

In line with this objective, the National Institutes of Health, in close cooperation with The National Institute on Aging and the National Institute of Arthritis and Musculoskeletal and Skin Diseases, has recently established a program called Mechanisms Mediating Osteoarthritis in Aging in an effort to improve and encourage the characterization of new and underutilized models in order to gain a deeper understanding of mechanisms that are involved in osteoarthritic progression.

Osteoarthritis is a common degenerative joint disease that usually affects the elderly population from 50 to 80 years old and above. The disease limits the mobility of the person and brings so much pain and inconvenience. It is often associated with mechanical abnormalities involving degradation of joints including articular cartilage and subchondral bone. The symptoms of this degenerative disease condition are joint pain, tenderness, stiffness, locking, and joint effusion.

The program aims to obtain a deeper understanding of the mechanisms that are involved in osteoarthritis through conducting research studies on genetically defined and modified mouse models, dogs, monkeys, and even archived human joints.

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Mechanisms Mediating Osteoarthritis in Aging
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About The Author The TopGovernmentGrants Editorial Staff maintains one the most comprehensive Websites offering information on government grants and federal government programs. The staff also provides resources to other Websites with information on grants for youth programs and home improvement grants.

Additional Resources

category - Health Grants

Center for Disease Control and Prevention: Training for States on Winnable Battles
The purpose of the Training for States on Winnable Battles program is to enable the CDC to offer training, educational materials, and technical assistance to legislative executives and administrative branches of states.

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National Institutes of Health: Expanding the Encyclopedia of DNA Elements in Human and Model Organisms
The National Institutes of Health, in cooperation with the National Human Genome Research Institute, has established a funding opportunity to support the Expanding the Encyclopedia of DNA Elements in Human and Model Organisms project.

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Planning Grants for Hubs of Interdisciplinary Research and Training in Global Environmental and Occupational Health Project
The National Institutes of Health has collaborated with the Centers for Disease Control and Prevention (CDC) to establish the Planning Grants for Hubs of Interdisciplinary Research and Training in Global Environmental and Occupational Health Project.

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Leadership Group for a Clinical Research Network on Antibacterial Resistance Program
In line with this mission, the National Institutes of Health has collaborated with the National Institute of Allergy and Infectious Diseases (NIAID) in an attempt to establish the Leadership Group for a Clinical Research Network on Antibacterial Resistance Program.

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