Mechanisms Mediating Osteoarthritis in Aging
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Initially, the program intends to support research studies that seek to explore the biological mechanisms that are associated with non-inflammatory joint degeneration, as seen in Osteoarthritis. These studies will consequently attempt to determine certain genes, biochemical pathways, and proteins that will contribute to the onset of joint degeneration.

This process will eventually enable researchers to identify the events and processes that will lead to joint degeneration, the functional characterization of proteins that are involved in the process, and the manner by which these gene products contribute to joint degeneration.

As a result, this deepened understanding could potentially lead to the timely prevention and more efficient treatment regimen for people suffering from Osteoarthritis.

The institutions and organizations that will be considered eligible to submit an application under the Mechanisms Mediating Osteoarthritis in Aging are the following:

a) Higher Education Institutions such as Public/State Controlled Institutions of Higher Education and Private Institutions of Higher Education

b) Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions

c) Nonprofit organizations other than institutions of higher education

d) For-Profit Organizations such as Small Businesses

e) State Governments, County Governments, City or Township Governments, Special District Governments, Indian/Native American Tribal Governments (Federally Recognized), and Indian/Native American Tribal Governments (Other than Federally Recognized)

f) Independent School Districts, Public Housing Authorities/Indian Housing Authorities, Native American Tribal Organizations (other than Federally recognized tribal governments), Faith-based or Community-based Organizations, and Regional Organizations.

The Department of Health and Human Services, the mother agency funding the Mechanisms Mediating Osteoarthritis in Aging, is the United States Federal government's leading agency that is largely responsible for ensuring the health of all Americans and the provision of fundamental human services to everyone needing to everyone needing such services.

Mechanisms Mediating Osteoarthritis in Aging
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Additional Resources



category - Health Grants

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The Office of Justice Programs has recently established the Justice and Mental Health Collaboration Training and Technical Assistance Program (JMHCP), wherein it seeks to increase public safety by encouraging collaboration between criminal justice, juvenile justice, and mental health and substance abuse treatment systems.


Exploratory Clinical Trials for Small Business Grant Program
The National Institutes of Health has formed a partnership with the National Institute of Neurological Disorders and Stroke (NINDS) in order to establish the Exploratory Clinical Trials for Small Business Grant Program wherein they aim to establish a vehicle for Small Business Concerns (SBCs) in the process of submitting Small Business Technology Transfer (STTR) grant applications for exploratory clinical trials directly to the NIND


National Institutes of Health: Expanding the Encyclopedia of DNA Elements in Human and Model Organisms
The National Institutes of Health, in cooperation with the National Human Genome Research Institute, has established a funding opportunity to support the Expanding the Encyclopedia of DNA Elements in Human and Model Organisms project.


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The National Institutes of Health, in close cooperation with the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), has established a program entitled Rheumatic Diseases Research Core Centers Project wherein they intend to solicit applications for the development of Research Core Centers concentrating on rheumatic diseases.






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