Predictive Lung Deposition Models for Safety and Efficacy of Orally Inhaled Drug Products Program.

by: Iola Bonggay

The United States Food and Drug Administration, otherwise referred to as the USFDA, an agency operating within the United States Department of Health and Human Services that is generally responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs, vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices, veterinary products, and cosmetics.

The USFA has recently formed a collaboration with the National Institutes of Health to establish the Predictive Lung Deposition Models for Safety and Efficacy of Orally Inhaled Drug Products Program.

The primary goal of the program is to develop computational fluid dynamics (CFD) model of orally inhaled drug products that can account for drug product characteristics and physiological parameters on total and regional deposition in the lungs.

This is all in conjunction with the USFDA's objective of developing a CFD model that will be capable of of predicting highly localized deposition of pharmaceutically relevant polydisperse aerosols from metered dose inhalers (MDIs) and dry powder inhalers (DPIs).

In addition, the results that will be derived from this study will then be utilized to create a linked CFD-compartment model that can predict the effects of lung deposition on safety (systemic exposure) and efficacy (local delivery) for locally acting orally inhaled drugs.

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Predictive Lung Deposition Models for Safety and Efficacy of Orally Inhaled Drug Products Program.
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About The Author Iola Bonggay is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. She also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Resources

category - Health Grants

Agriculture and Food Research Initiative: National Institute of Food and Agriculture Fellowships Grant Program
The Agriculture and Food Research Initiative grant program revolves around the premise of providing funds to both fundamental and applied research studies, education, and extension that would hopefully address concerns related to food and agricultural sciences.

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Peer Reviewed Cancer Career Development Award Program
In keeping with this mission, the Department of the Army has established the Peer Reviewed Cancer Career Development Award Program in an attempt to stimulate the next generation of cancer research studies by providing new and early career investigator opportunities that would lead to innovative, cutting-edge research developments for the prevention, early detection, and treatment of cancer.

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Targeting Persistent HIV Reservoirs Grant Program
In keeping with this mission, the National Institutes of Health has recently formed a partnership with the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Mental Health (NIMH) in order to establish the Targeting Persistent HIV Reservoirs Grant Program.

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Grants form the Department of Health and Human Services
In the year 1979, the Department of Health and Human Services, otherwise known as HHS, was established in an effort to protect the health of all Americans and to provide essential human services to everyone, especially to those who are least capable of helping themselves.

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